Emphasizes basic principles behind the methods of bioinformaticsDiscusses the limitations and range of applicability of each methodologyPresents material on proteomics not found in other basic bioinformatics textsIncludes references to historical and key articles as well as useful Internet sites Presenting an overview of basic methods, Introduction to Bioinformatics provides information that guides readers from elucidation and analysis of a genomic sequence to the prediction of a protein structure and the identification of the molecular function. The author emphasizes the basic principles that underlie the methods, rather than tools and discusses the limitations and range of applicability for each methodology. The treatment includes material on proteomics that is not found in any other basic bioinformatics textbook. Requiring only a limited mathematical and statistical background, the text includes references to historical and key articles while offering pointers to useful Internet sites.