This book explains the systematic structure and practical use of the new SQC application that systematically and organizationally enhances the corporate management key for the 21st century. Departing from the conventional statistical application of SQC, this book explains the SQC application for scientific problem solving and its structural framework in which SQC is utilized for discovering the cause and effect relation from the gap between a theory and the actual, eliciting a new fact and finding, and establishing a general solution that contributes to development of innovative technology. It also reports case studies in which management technology issues were solved at a manufacturer, Toyota Motor Corporation, and verifies that: 1. Application of Science SQC promotion cycle that enables creative human resources development enhances problem solving skills of the staff and business process quality, and contributes to establishing core technology; 2. Science SQC is applicable to a wide range of business types including planning, design, engineering, production, sales, and administration. In the earlier thesis, "SQC Application for Developing Individual Techniques (1992)", the author introduced an example of "SQC Renaissance" in which SQC was effectively utilized for solving engineers' immediate problems. Further, in the thesis, "Science SQC-Innovation of Business Process Quality 2OOO)", the author proposed approaches and procedures of scientific application of SQC (Science SQC) and verified their effectiveness by introducing case studies that solved contemporary engineering problems.