Various peptides native to the brain and the spinal cord, as well as various synthetic peptides, peptide analogues and peptidomimetics could be useful in the treatment of diseases of the central nervous system. This book provides an overview of the role and neuropharmaceutical potential of these peptides, and discusses the state of the art and future trends in the use of peptide pharmacotherapy involving the brain. Written for: Neuroscientists; pharmaceutical industry (involved in drug development and drug delivery); researchers from neurochemistry, biochemistry, pharmacology, physiology, neurosurgery Keywords: CNS blood-brain-barrier drug delivery drug development neuropeptides pharmacotherapy