In this definitive reference, the author lends 50 years of experience in the subject to Paramecium Genetics. Paramecia were among the first organisms used to clarify genetic mechanisms, and though they have been overtaken by other organisms in genetics research, it is still of historical interest to geneticists. The text is written in an accessible, informal style and incorporates historical aspects. It covers features of the organism itself, general morphology and reproduction, mating types, methods of genetic analysis, endosymbionts and mitochondria, immobilization antigens, micro-and macronuclei, ribosomal DNA, telomeres, behavioral mutants and epigenetic phenomena.