Leaders in the field provide the latest information on the diagnosis and management of high-grade gliomas in this new groundbreaking text. The entire spectrum of issues pertaining to high-grade gliomas is covered, from the basics of clinical characteristics and management to the state-of-the-art in diagnosis and therapeutics. Forefront areas of clinical investigation are also covered with the promise of leading us to the treatments of tomorrow. The authors evaluate the latest molecular diagnostic techniques and their use with current histology. They later explore the most current imaging techniques for the diagnosis and monitoring of treatment, as well as the latest treatment strategies including surgery, radiation, and cytotoxic chemotherapy. All physicians treating brain tumors including neurosurgeons, neurologists and radiation oncologists will benefit from the coverage herein of the meaningful advances in our understanding of the biology of high-grade gliomas that are now leading to better, more rational, patient-specific treatments.