Handbook of Proteolytic Enzymes 2 Vols

Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3D colour structures and much more.The only comprehensive book on proteolytic enzymesIncludes 671 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses, including those that are currently major targets of pharmaceutical researchAccompanying CD-ROM provides useful search facilitiesPraise for the first edition:'The CD-ROM format is ideal for the presentation of this mass of structured information. There are a number of useful search facilities, including the unique Specificity Search procedure developed for this project..... Nethertheless with excellent diagrams, useful search facilities and extensive hyperlinks, the CD-ROM is far too useful a resource for any reader who is used to the vagaries of software to be put off by minor glitches....' -BIOCHEMICAL EDUCATION' The Handbook of Proteolytic Enzymes is a much needed reference book in the field of peptidases. Not only does it provide a wealth of information for the vast majority of the individual enzymes discussed, but also it shows vividly the relationships among members of families and clans within the 4 major classes.' -Michael N.G. James, MRC Canada, Group in Protein Structure and Function, Department of Biochemistry in PROTEIN SCIENCE'...a massive and definitive compilation of information on proteolytic enzymes and will no doubt be the standard work for years to come...the information collected here will be of great value to scientists working in practically the whole of biology as well as to the biotechnology industry...' -BIOCHEMICAL EDUCATION' The present Handbook of Proteolytic Enzymes by Barrett, Rawlings, and Woessner is an important and heroic accomplishment in this regard, as for the first time in the history of enzymology it presents a rather complete hierarchical reference of the chemical and biological properties of proteases. This work has been the product of over [550] contributors, most of who have demonstrated their knowledge and familiarity with one or the other of the [more than] 500 proteases described in this work. The list will undoubtedly grow further but even at this stage, I consider it an indispensable resource for the practicing enzymologists, protein chemists and molecular biologists generally. The authors, their contributors and the publisher have rendered a most valuable service to the students, scholars and general practitioners in making this compilation available at this time and deserve a round of applause for having done so with remarkable skill and devotion.'-Hans Neurath, Professor Emeritus of Biochemistry, University of Washington Seattle, Washington