Chemical Biology

Chemical Biology has become the new buzzword in organic chemistry and in the life sciences, describing a new era in the interplay between the two disciplines and still on the rise. By synthesizing tailor-made libraries of bioactive chemical compounds, many hitherto unapproachable problems in cell and molecular biology can now be systematically addressed, such as in signaling or cell development. This same approach has greatly expanded the potential for the discovery of novel small molecule drugs. Edited by the world leaders in the field, this three-volume handbook begins with a discussion of the use of small molecules to explore biology. They then go on to look at discovering small molecule probes for biological mechanisms and expanding the scope of chemical synthesis. Further sections cover chemical informatics, drug discovery and systems biology, and the whole work is rounded off by the outlook and perspectives for this field. No academic institution or pharmaceutical company can possibly miss out on this highly authoritative work.