Provides a practical understanding of the unique and volatile physiology of the neonate and child;it fully examines the developmental changes which occur, which affect the response of numerous manipulations employed during by-pass, such as hypothermia, haemodilution, acid-base management, anticoagulation and anaesthesia. Jonas and Elliott are based at Boston's Children's Hospital and Great Ormond Street, London respectively, undoubtedly the most prestigious of units in this field worldwide and the source of many developments. Their expertise and that of over twenty internationally recognized contributors, will ensure that this book sets the standard of knowledge required for the practice of cardiopulmonary bypass in children.