Because the concept and discoveries of cancer stem cells are relatively new, scientists and researchers (especially those not directly involved in these breakthroughs) need an introduction to this dynamic area. This book presents a consolidated account of the research done to date and recent progresses in the studies of cancer stem cells. Such a presentation facilitates a better understanding of and draws attention to stem cell and cancer biology two fields that enhance, move, and evolve into each other continuously. With a basis in the research performed in the authors lab, this book serves as a primer for new researchers in the field of cancer biology. It provides an informative study in designing approaches to apply stem cell principles to cancer biology while offering an overview of the challenges in developing combination stem and cancer biology targets for therapeutics.