The only reference of its kind in the field ! The new edition of this definitive resource examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. It describes the presentation, differential diagnosis, course, management, and prognosis of every major condition. Drs. Cassidy and Petty have meticulously revised their masterwork to integrate important new scientific advances and clinical developments.Features exhaustive reviews of the major clinical syndromes, describing the complex web of symp-toms, signs, and lab abnormalities characteristic of these disorders in order to make diagnosis and treatment easier Grounds treatment protocols in the best scientific evidence available today Establishes an internationally accepted nosography of classification criteria based on the ACR, EULAR, and ILAR criteria Clarifies complex concepts and demonstrates key techniques with 400 illustrations, which include new figures and a new four-colour insert Integrates the knowledge and experience of the founding fathers of pediatric rheumatology as well as a who's who of international experts in the fieldExpanded coverage of immunogenetics, detailing advances from the sequencing of the human genome and a new understanding of immunologic mechanisms of inflammatory disease Enhanced discussions of pharmacology, drug therapy, and systemic connective tissue diseases A new chapter on The Febrile Syndromes The expertise of two new associate editors, Ronald M. Laxler and Carol B.Lindsley