Protein-carbohydrate Interactions in Infectious Disease

Protein-carbohydrate interactions is an exciting area of research with huge potential for development and exploration. These interactions are both widespread and diverse in biological processes and many play a crucial role in cellular recognition, attachment and adhesion. This is particularly true for host-pathogen interactions that lead to infectious diseases, as the surfaces of cells and pathogens display complex carbohydrate structures and carbohydrate-binding proteins on their surface. "Protein-Carbohydrate Interactions in Infectious Diseases" is part of the "Biomolecular Science" Series and provides a comprehensive overview of the subject, with contributions from leading experts in the field. Beginning with a general introduction, subsequent sections include: atomic basis of protein-carbohydrate interactions; structures and roles of Pseudomonas areuginosa lectins; protein-carbohydrate interactions in enterobacterial infections; Retrocylcins: miniature lectins with potent antiviral activity; C-type lectin receptors that regulate pathogen recognition through the recognition of carbohydrates; synthetic carbohydrate-based anti-malarial vaccines and glycobiology. With full colour throughout and an extensive bibliography, this book is ideal for researchers interested in the area.