This volume brings formal coherence to the overwhelming mass of prints published in sixteenth-century Rome. It is introductory in scope and does not attempt to include every print published by every publisher. The aim is to provide an overview of who was publishing what prints and when over the course of the sixteenth century. The five chapters provide an outline of the history of print publishing while the appendices serve to clarify chronologies and reveal groupings and patterns. A document central to this book deserves some comment. The record of the hearing into the murder of Gerolamo da Modena provided an opportunity to meet a number of the publishers, printers, and engravers at work in Rome in the decades after the mid-century and to understand better their lives, activities, and relationships.