This unique text offers practitioners both a review of the basic concepts of epidemiology, statistics, and clinical trials and a discussion of the epidemiologic aspects of many neurological diseases. Much of the information contained in Principles of Neuroepidemiology, such as cost-effectiveness analyses, has been difficult for busy practitioners to find in the past. By reading this book, physicians will acquire the skills they need to critically evaluate randomized trials that have affected the clinical practice of neurology.The editors have brought together a highly regarded panel of contributors to lend their expertise to this text. The first section is devoted to the fundamentals of epidemiology, clinical trial design and analyses, tests of significance, quality of life scales, and recent therapeutic advances. The second section focuses on specific neurologic diseases, including defining outcomes and cost effectiveness. Epidemiologic issues have been more topical in today's medical environment, and this book is needed to help clinicians understand the terminology and stay abreast of recent advances gained through neurologic trials.