Completely rewritten and updated for its Fourth Edition, this best-selling text is a comprehensive, clear, concise, and easy-to-understand introduction to cardiovascular diseases. It is written by internationally recognized Harvard Medical School faculty and select medical students, and is the best text to bridge basic physiology with clinical care of patientThis edition provides updated coverage of pathogenesis of atherosclerosis, pathophysiology of acute coronary syndromes, mechanisms of heart failure, molecular mechanisms