Oral Anticoagulants

Warfarin and related drugs have been used for over a half a century in prevention and treatment of thrombotic disorders. Only recently, however, has their clinical role been firmly established by randomized studies and their benefit/risk ratio improved by lower dose therapy with improvement in laboratory monitoring.

Oral Anticoagulants is the first comprehensive, practical survey of the subject available. An international team of recognized experts provide detailed coverage on the mode of action; clinical pharmacodynamics; magnitude and sources of variability in individual response to oral anticoagulants; methods of individualizing dosing regiments; laboratory monitoring; and comparison between the different currently prescribed oral anticoagulants.