This reference presents a wide variety of mass spectrometry methods used to explore structural mechanisms, protein dynamics and interactions between proteins. Preliminary chapters cover mass spectrometry methods for examining proteins and are then followed by chapters devoted to presenting very practical, how-to methods in a detailed way. Methods include deuterium exchange, covalent labeling, footprinting, plistex, and computational approaches. The inclusion of coverage of footprinting and plistex specifically, sets the book apart from the competition. # Presents a wide variety of mass spectrometry methods used to explore structural mechanisms, protein dynamics and interactions between proteins.# Preliminary chapters cover mass spectrometry methods for examining proteins and are then followed by chapters devoted to presenting very practical, how–to methods in a detailed way.# Includes footprinting and plistex specifically, setting this book apart from the competition.