Research on ion channels now crosses most traditional subject boundaries and involves a wide range of approaches including some of the latest techniques in biochemistry and molecular biology, as well as advanced electrophysiology and biophysics. This volume describes up-to-date practical information for some of the most essential and exciting approaches currently available. Topics covered include patch-clamp recording, concepts of single-channel analysis, channel cloning, channel structure, and signal transduction systems. This will be an invaluable source of practical information for researchers from a variety of academic backgrounds, whose areas of interest might include membrane biology, membrane ion transport, and membrane transport proteins.