Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD) is one of the most prevalent genetic disorders of childhood and currently stands as an incurable condition. This authoritative guide provides a clear overview of the latest current and experimental approaches to the treatment of DMD and examines the clinical, genetic, and pathophysiological aspects of the disease in the context of emerging therapeutic modalities. Surveying advances at the forefront of the discipline, this expertly written source: discusses challenges to the development of treatments for DMD contains chapters on diagnostic modalities and innovations in molecular diagnostics focuses on viral and non-viral gene therapy research, as well as promising stem cell therapeutics and potential targets for conventional drug approaches considers intersections between different approaches to treatment and within the broader scope of the emerging field of regenerative medicine highlights pathways for future research in the field. The only available source on the subject, this reference emphasizes the importance of accurate diagnosis, carrier detection, and genetic counseling, and supplies state-of-the-art contributions on pharmacological interventions, regenerative medicine, and gene therapy.