Challenges for the treatment of valvular heart disease include the growing need for effective yet less invasive interventions and therapies to treat these progressive conditions. With the development of potential new treatments, it is crucial for cardiac physicians to be well informed on the pathophysiology, assessment, treatment options and their outcomes of valvular diseases. Written by a highly experienced and internationally recognized group of cardiologists, cardiac surgeons, and researchers, Valvular Heart Disease offers insights into the widely varying hemodynamic effects and clinical course of heart valve conditions, as well as the contemporary management of these conditions. Offering a broad perspective on these diseases, Valvular Heart Disease expands on the recent guidelines developed by the major heart societies in the United State and Europe.Table of contents 1. Morphologic Aspects of Valvular Heart Disease William C. Roberts, MD and Jong Mi Ko, BA 2. Cellular Pathogenesis of Degenerative Valvular Heart Disease: From Calcific Aortic Stenosis to Myxomatous Mitral Valve Disease Nalini M. Rajamannan, MD 3. Ventricular Adaptation to Valvular Stenosis and Regurgitation Blasé A. Carabello, MD 4. Physical Examination in Valvular Heart Disease Brian P. Griffin, MD and Carmel M. Halley, MD 5. Clinical Hemodynamics of Valvular Heart Disease Thomas M. Bashore, MD 6. Echocardiographic Assessment of Native Valve Function Gail E. Peterson, MD and Lisa Forbess, MD 7. Aortic Stenosis Paul Sorajja, MD and Rick A. Nishimura, MD 8. Aortic Regurgitation Vera H. Rigolin, MD and Robert H. Bonow, MD 9. Mitral Stenosis Nazanin Moghbeli, MD, MPH and Howard C. Herrmann, MD 10. Mitral Regurgitation Maurice Enriquez-Sarano, MD, Vuyisile T. Nkomo, MD and Hector I Michelena, MD 11. Tricuspid Stenosis and Regurgitation Charles J. Bruce, MBChB, Heidi M. Connolly, MD and Patricia A. Pellikka, MD 12. Pulmonic Stenosis and Regurgitation Carlos E. Ruiz, MD, PhD and Laurence M. Schneider, MBbCh 13. Contemporary Considerations in Aortic Valve Replacement Therapy B. Zane Atkins, MD, Neal D. Kon, MD and G. Chad Hughes, MD 14. Contemporary Considerations in Mitral Valve Repair and Replacement Donald D. Glower, MD 15. Pulmonic and Tricuspid Valve Surgery Sapan S. Desai, MD. PhD and Andrew J. Lodge, MD 16. Medical Therapy of Valvular Heart Disease Sahil A. Parikh, MD and Patrick T. O’Gara, MD 17. Percutaneous Valve Replacement John G Webb, MD and Lukas Altwegg, MD 18. Percutaneous Valvuloplasty and Repair Ted Feldman, MD 19. Post-operative Complications of Heart Valve Surgery Aslan T. Turer, MD, Thomas H. Gehrig, MD and J. Kevin Harrison, MD 20. Prosthetic Valve Dysfunction Philippe Pibarot, DVM, PhD, Jean G. Dumesnil, MD and Julien Magne, BSc 21. Infective Endocarditis Andrew Wang, MD and Christopher H. Cabell, MD 22. Non-cardiac Surgery and Exercise in Valvular Heart Disease Stephen A. Hart, BS and Richard A. Krasuski, MD 23. Pregnancy in Valvular Heart Disease Cary Ward, MD and Andra H. James, MD