Polyamine Cell Signaling

Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research presents current state-of-the-art findings relevant to cellular and molecular functions of polyamines as well as providing the underlying conceptual basis and knowledge regarding potential therapeutic targeting polyamines and polyamine metabolism leading to the development of new therapeutic approaches for cancers and other diseases. Divided into four main sections that include: polyamines in signal transduction of cell proliferation; polyamines in cellular signaling of apoptosis, carcinogenesis, and cancer therapy; polyamines in cell motility and cell-cell interactions; and polyamine homeostasis and transport, these topics are addressed by internationally recognized experts in their respective fields. This timely guide provides the whole picture of polyamines-past, present, and potential future and offers a wealth of information regarding basic knowledge and current progress on cellular functions of polyamines and their potential clinical applications in cancer therapy. For investigators in the fields of polyamines, physiology, pharmacology, and cancer research, Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research serves as a foundation based on research and addresses the potential for subsequent applications in clinical practice.