General and Systematic Pathology is a highly acclaimed textbook, written and designed for students of medicine and related health science subjects. It presents pathology in the context of modern cellular biology and clinical practice. This comprehensive text begins with the principles of pathology and the mechanisms of disease before covering systematic pathology. For this edition considerable care has been taken to further refine and improve the contents. The editors have responded to detailed feedback provided by an International Advisory Board. Further Reading sections have been extended and annotated and key web sites have been included. In response to the integration between the scientific and clinical parts of the courses, is a new feature `Mechanism of treatment' boxes. These identify which part of the pathological process is influenced by various treatments and how.