Gene Family Targeted Molecular Design

As research progresses and information continues to proliferate in the field of molecular design for therapeutic use, there is a need for a reference that brings current theory and proven practice together in a how-to volume This reference guides scientists new to the field on how to design small molecules that interact with critical protein targets. The chapters condense useful material into a manageable format which is carefully organized and presented. A reference, how to book on compound design for generating small molecules that interact with important protein targets would be useful for advanced undergraduate or graduate students and new researchers in the medicinal chemistry area. There is a tremendous amount of literature on the topic of molecular biochemistry, and very little work has been done to condense the information into a manageable format as practical guidance for a chemist to get started in the area of designing compounds that intervene in important points of disease pathology. Overwhelming amounts of information are available in each research area making it a daunting task to do cross comparisons of the different gene families. Synthetic, structural, computational, and medicinal chemists in academia, biomedical companies, and the pharmaceutical industry would benefit from this type of book. Colleagues of these chemists in complementary fields (enzymologists, pharmacologists, physicians, technical assistants, pharmacists, biophysicists as well as students studying in these areas) that wish to understand more about the drug design process might also be interested in sections of the book for protein characteristic differences, challenges and successes in compound design.