Although often absent from the considerations of philosophers, sociologists and anthropologists, the material dimension plays an important and even essential role in the practices of the sciences. This volume begins to redress this absence by bringing together four prominent figures who make technoscience, or science embodied in its technologies, a central theme of their work. Through lively personal interviews and substantive essays, the ideas of Andrew Pickering, Don Ihde, Donna Haraway and Bruno Latour are brought to bear on the question of materiality in technoscience. The work of these theorists is then compared and critiqued in essays by colleagues.