Cell Culture and Upstream Processing

Upstream processing refers to the production of proteins by cells genetically engineered to contain the human gene which will express the protein of interest. The demand for large quantities of specific proteins is increasing the pressure to boost cell culture productivity, and optimising bioreactor output has become a primary concern for most pharmaceutical companies. Each chapter in Cell Culture and Upstream Processing is taken from a presentation at the highly acclaimed IBC conferences and describe ways for scientists to improve yield and optimise the cell culture production process for biopharmaceuticals, by focusing on safety, quality, economics and operability and productivity issues.