Boronic Acids

In the past decade, organoboronic acids and boronic esters have become an extremely important class of compounds. Stable and safe to handle, these green compounds embrace a wide range of applications including their use as reagents and catalysts in organic synthesis, as probes and sensors in chemical biology, and as therapeutic drugs. Here, for the first time, the full story of organoboronic acids is presented in one comprehensive handbook. Professor Dennis Hall, a rising star in the field, is joined by a select group of expert authors to provide 13 chapters that cover all modern aspects of boronic acid derivatives. This book is an invaluable reading for organic, organometallic, and medicinal chemists. From the Contents: Structure, properties, and preparation of boronic acid derivatives Metal-catalyzed borylation of alkanes and arenes Cross-coupling reactions of areneboronic acids or esters with aromatic electrophiles Rhodium-catalyzed additions of boronic acids to alkenes and carbonyl compounds Copper-promoted C-heteroatom bond cross-coupling reactions with boronic acids Preparation of allylboronates and recent applications in organic synthesis Nucleophilic addition reactions of aryl and alkenylboronic acids to imine derivatives Alpha-haloalkylboronic esters in asymmetric synthesis Cycloadditions and other additions to alkenyl- alkynyl-, and dienylboronic esters Organoboronic acids and organoborinic acids as catalysts in organic synthesis Oxazaborolidines as asymmetric inducers for the reduction of ketones and ketimines Boronic acid based receptors and sensors for saccharides Biological and medicinal applications of boronic acids